Hope this strikes a funny cell:
This post was inspired by my young cousin Brian, good pick buddy.
Laughter and the brain:
A link between laughter and healthy function of blood vessels was first reported in 2005 by researchers at the University of Maryland Medical Center with the fact that laughter causes the dilatation of the inner lining of blood vessels, the endothelium, and increases blood flow. Dr. Michael Miller (University of Maryland) and William Fry (Stanford), theorize that beta-endorphin like compounds released by the hypothalamus activate receptors on the endothelial surface to release nitric oxide, thereby resulting in dilation of vessels. Other cardioprotective properties of nitric oxide include reduction of inflammation and decreased platelet aggregation.
Scientists have shown that parts of the limbic system are involved in laughter. This system is involved in emotions and helps us with functions necessary for humans’ survival. The structures in the limbic system that are involved in laughter: the hippocampus and the amygdala.
The December 7, 1984, Journal of the American Medical Association describes the neurological causes of laughter as follows:
- “Although there is no known ‘laugh center’ in the brain, its neural mechanism has been the subject of much, albeit inconclusive, speculation. It is evident that its expression depends on neural paths arising in close association with the telencephalic and diencephalic centers concerned with respiration. Wilson considered the mechanism to be in the region of the mesial thalamus, hypothalamus, and subthalamus. Kelly and co-workers, in turn, postulated that the tegmentum near the periaqueductal grey contains the integrating mechanism for emotional expression. Thus, supranuclear pathways, including those from the limbic system that Papez hypothesised to mediate emotional expressions such as laughter, probably come into synaptic relation in the reticular core of the brain stem. So while purely emotional responses such as laughter are mediated by subcortical structures, especially the hypothalamus, and are stereotyped, the cerebral cortex can modulate or suppress them.”
- Video uploaded by U Tube user-Man1acProduction